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Presynaptic NMDA receptors get into the act

Nature Neuroscience volume 7, pages 419420 (2004) | Download Citation

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In a new form of synaptic plasticity, depolarization of Purkinje cells increases the frequency of mini GABAergic IPSCs, via glutamate acting as a retrograde messenger on presynaptic NMDA receptors on the terminals of cerebellar interneurons.

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Affiliations

  1. Anastassios V. Tzingounis and Roger A. Nicoll are at the Departments of Cellular and Molecular Pharmacology and Physiology, University of California at San Francisco, San Francisco, California 94943, USA. nicoll@cmp.ucsf.edu

    • Anastassios V Tzingounis
    •  & Roger A Nicoll

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DOI

https://doi.org/10.1038/nn0504-419

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