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The merging of the senses: integration of subthreshold taste and smell

Abstract

Central neural integration of sensory input from different modalities is a prerequisite for many types of perception and behavior. One of the best examples of such an integrative process may be flavor perception, whereby activation in two peripherally distinct neural systems, olfaction and gustation, combines to give rise to a unified oral sensation. Here we used a psychophysical method to show cross-modal summation of subthreshold concentrations of selected gustatory and olfactory stimuli, thus demonstrating that central neural integration of taste and smell inputs generates a representation of flavor perception.

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Figure 1: Median percent change from baseline benzaldehyde threshold in experiments 1–3.

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References

  1. Gielen, S. C., Schmidt, R. A. & Van Der Heuvel, P. J. Percept. Psychophys. 34, 161–168 (1983).

    Article  CAS  Google Scholar 

  2. Wallace, M. T., Wilkinson, L. K. & Stein, B. E. J. Neurophysiol. 76, 1246–1266 (1996).

    Article  CAS  Google Scholar 

  3. Sparks, D. L. & Groh, J. M. in The Cognitive Neurosciences (ed. Gazzaniga, M. S.) 565–584 (MIT Press, Cambridge, Massachusetts, 1995).

    Google Scholar 

  4. Stevens, J. C. Physiol. Behav. 62, 1137–1143 (1997).

    Article  CAS  Google Scholar 

  5. Guadagni, D. G., Buttery, R. G., Okano, S. & Burr, H. K. Nature 200, 1288–1289 (1963).

    Article  CAS  Google Scholar 

  6. Murphy, C., Cain, W. S. & Bartoshuk, L. M. Sens. Process. 1, 204–211 (1977).

    CAS  Google Scholar 

  7. Wetherill, G. B. & Levitt, H. Br. J. Math. Stat. Psychol. 18, 1–10 (1965).

    Article  CAS  Google Scholar 

  8. Frank, R. A. & Byran, J. Chem. Senses 13, 445–455 (1988).

    Article  CAS  Google Scholar 

  9. Schifferstein, H. N. & Verlegh, P. W. Acta Psychol. 94, 87–105 (1996).

    Article  CAS  Google Scholar 

  10. Fowler, C. A. & Dekle, J. A. J. Exp. Psychol. Hum. Percept. Perform. 17, 816–828 (1991).

    Article  CAS  Google Scholar 

  11. Krushel, L. A. & van der Kooy, D. J. Comp. Neurol. 270, 39–54 (1988).

    Article  CAS  Google Scholar 

  12. Rolls, E. T. & Baylis, L. L. J. Neurosci. 14, 5437–5452 (1994).

    Article  CAS  Google Scholar 

  13. Whalen, P. J. Curr. Dir. Psychol. Sci. 7, 177–188 (1998).

    Article  Google Scholar 

  14. Schul, R., Slotnick, B. M. & Dudai, Y. Behav. Neurosci. 110, 760–765 (1996).

    Article  CAS  Google Scholar 

  15. Kapp, B. S., Whalen, P. J., Supple, W. F. & Pascoe, J. P. in The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction (ed. Aggleton, J. P.) 229–254 (Wiley-Liss, New York, 1992).

    Google Scholar 

Download references

Acknowledgements

This work was supported by NIH grants RO1-DC03704 (P.D.) and R29-DC02995 (P.B.). We thank Ines Rodriguez for assistance with data collection.

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Correspondence to P. Dalton.

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Dalton, P., Doolittle, N., Nagata, H. et al. The merging of the senses: integration of subthreshold taste and smell. Nat Neurosci 3, 431–432 (2000). https://doi.org/10.1038/74797

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