Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Preventing dehydration during sleep

Vasopressin release increases late in sleep. Suprachiasmatic clock neurons modulate osmosensory synapses onto vasopressin neurons to facilitate osmoregulated vasopressin release, reports a study in this issue. This explains the increased late-night vasopressin release, and such facilitation prevents dehydration during sleep.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Circadian regulation of an osmoregulatory circuit.

References

  1. Reppert, S.M. & Weaver, D.R. Nature 418, 935–941 (2002).

    Article  CAS  PubMed  Google Scholar 

  2. Takahashi, J.S., Hong, H.K., Ko, C.H. & McDearmon, E.L. Nat. Rev. Genet. 9, 764–775 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Barnard, A.R. & Nolan, P.M. PLoS Genet. 4, e1000040 (2008).

    Article  PubMed  PubMed Central  Google Scholar 

  4. Trudel, E. & Bourque, C.W. Nat. Neurosci. 13, 467–474 (2010).

    Article  CAS  PubMed  Google Scholar 

  5. Ciura, S. & Bourque, C.W. J. Neurosci. 26, 9069–9075 (2006).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Egan, G. et al. Proc. Natl. Acad. Sci. USA 100, 15241–15246 (2003).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Bourque, C.W. Nat. Rev. Neurosci. 9, 519–531 (2008).

    Article  CAS  PubMed  Google Scholar 

  8. Bhumbra, G.S., Lombardelli, S., Gonzalez, J.A., Parsy, K.S. & Dyball, R.E. J. Neuroendocrinol. 21, 935–945 (2009).

    Article  CAS  PubMed  Google Scholar 

  9. Forsling, M.L. Exp. Physiol. 85 Spec No, 179S–186S (2000).

  10. Karolczak, M., Korf, H.W. & Stehle, J.H. Endocrine 27, 89–100 (2005).

    Article  CAS  PubMed  Google Scholar 

  11. Turek, F.W. et al. Science 308, 1043–1045 (2005).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Woon, P.Y. et al. Proc. Natl. Acad. Sci. USA 104, 14412–14417 (2007).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Christopher S Colwell.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Colwell, C. Preventing dehydration during sleep. Nat Neurosci 13, 403–404 (2010). https://doi.org/10.1038/nn0410-403

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn0410-403

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing