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It's about time for thalamocortical circuits

Nature Neuroscience volume 10, pages 400–402 (2007)Cite this article

The timing of thalamocortical excitation and inhibition is critical to local microcircuits. Two new papers shed light on the development and performance of a somatosensory microcircuit that regulates the integration of thalamic inputs.

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Figure 1: Development and function of the thalamocortical microcircuit.

References

  1. Phillips, J.R., Johnson, K.O. & Hsiao, S.S. Proc. Natl. Acad. Sci. USA 85, 1317–1321 (1988).

    Article  CAS  Google Scholar 

  2. Gabernet, L., Jadhav, S.P., Feldman, D.E., Carandini, M. & Scanziani, M. Neuron 48, 315–327 (2005).

    Article  CAS  Google Scholar 

  3. Daw, M., Ashby, M. & Isaac, J. Nat. Neurosci. 10, 453–461 (2007).

    Article  CAS  Google Scholar 

  4. Cruikshank, S., Lewis, T. & Connors, B. Nat. Neurosci. 10, 462–468 (2007).

    Article  CAS  Google Scholar 

  5. Gibson, J.R., Beierlein, M. & Connors, B.W. Nature 402, 75–79 (1999).

    Article  CAS  Google Scholar 

  6. Inoue, T. & Imoto, K. J. Neurophysiol. 96, 1746–1754 (2006).

    Article  Google Scholar 

  7. Pinto, D.J., Brumberg, J.C. & Simons, D.J. J. Neurophysiol. 83, 1158–1166 (2000).

    Article  CAS  Google Scholar 

  8. Wilent, W.B. & Contreras, D. Nat. Neurosci. 8, 1364–1370 (2005).

    Article  CAS  Google Scholar 

  9. Swadlow, H.A. & Gusev, A.G. J. Neurophysiol. 83, 2802–2813 (2000).

    Article  CAS  Google Scholar 

  10. Agmon, A., Hollrigel, G. & O'Dowd, D.K. J. Neurosci. 16, 4684–4695 (1996).

    Article  CAS  Google Scholar 

  11. Agmon, A. & Connors, B.W. Neuroscience 41, 365–379 (1991).

    Article  CAS  Google Scholar 

  12. Fox, K. J. Neurosci. 12, 1826–1838 (1992).

    Article  CAS  Google Scholar 

  13. Crair, M.C. & Malenka, R.C. Nature 375, 325–328 (1995).

    Article  CAS  Google Scholar 

  14. Bruno, R.M. & Simons, D.J. J. Neurosci. 22, 10966–10975 (2002).

    Article  CAS  Google Scholar 

  15. Trussell, L.O. Annu. Rev. Physiol. 61, 477–496 (1999).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Division of Biology, Section of Neurobiology, University of California San Diego, 9500 Gilman Drive, La Jolla, 92093-0634, California, USA

    Court Hull & Massimo Scanziani

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  1. Court Hull
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  2. Massimo Scanziani
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Hull, C., Scanziani, M. It's about time for thalamocortical circuits. Nat Neurosci 10, 400–402 (2007). https://doi.org/10.1038/nn0407-400

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