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Alzheimer disease, in living color

A new study shows that amyloid plaques tagged with fluorinated ligand can be detected with 19F MRI in transgenic mice. The superior signal to noise of this technique is a major step toward visualizing the histopathology of Alzheimer disease in living patients.

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Figure 1

Debbie Maizels

References

  1. Higuchi, M. et al. Nat. Neurosci. 8, 527–533 (2005).

    Article  CAS  Google Scholar 

  2. Klunk, W.E. et al. Ann. Neurol. 55, 306–319 (2004).

    Article  CAS  Google Scholar 

  3. Shoghi-Jadid, K. et al. Am. J. Geriatr. Psychiatry 10, 24–35 (2002).

    Article  Google Scholar 

  4. Small, S. et al. Neuron 28, 653–664 (2000).

    Article  CAS  Google Scholar 

  5. Jack, C.R. Jr. et al. Magn. Reson. Med. 52, 1263–1271 (2004).

    Article  Google Scholar 

  6. Lee, S.P., Falangola, M.F., Nixon, R.A., Duff, K. & Helpern, J.A. Magn. Reson. Med. 52, 538–544 (2004).

    Article  Google Scholar 

  7. Skovronsky, D.M. et al. Proc. Natl. Acad. Sci. USA 97, 7609–7614 (2000).

    Article  CAS  Google Scholar 

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Small, S. Alzheimer disease, in living color. Nat Neurosci 8, 404–405 (2005). https://doi.org/10.1038/nn0405-404

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