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Timing isn't everything

Synaptic long-term potentiation and depression are determined by the frequency and timing of coactivated synapses. A new model explains many experimental plasticity observations and allows new predictions about neural circuit function.

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Figure 1: Membrane potential–based rules for LTP and LTD.


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Correspondence to Nelson Spruston.

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Spruston, N., Cang, J. Timing isn't everything. Nat Neurosci 13, 277–279 (2010).

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