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Plateau properties in pain pathways

A new paper shows that excitatory and inhibitory neuromodulators can change the firing properties of spinal cord neurons, with implications for pain processing.

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Figure 1: Three different firing patterns found in deep dorsal horn neurons.
Figure 2: Cells with the three firing patterns shown in Fig. 1 have different responses to the same input.

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Marder, E. Plateau properties in pain pathways. Nat Neurosci 6, 210–212 (2003). https://doi.org/10.1038/nn0303-210

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