Many aspects of sleep, including the how and why, are still mysterious, especially its relationship to learning and memory. A new study suggests that sleep may serve to reset synaptic potentiation, linking it to homeostatic plasticity.
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Vyazovskiy, V.V., Cirelli, C., Pfister-Genskow, M., Faraguna, U. & Tononi, G. Nat. Neurosci. 11, 200–208 (2008).
Blanco-Centurion, C. et al. J. Neurosci. 26, 8092–8100 (2006).
Stickgold, R. & Walker, M.P. Sleep Med. 8, 331–343 (2007).
Korman, M. et al. Nat. Neurosci. 10, 1206–1213 (2007).
Huber, R., Ghilardi, M.F., Massimini, M. & Tononi, G. Nature 430, 78–81 (2004).
Huber, R. et al. PLoS ONE 2, e276 (2007).
Turrigiano, G. Curr. Opin. Neurobiol. 17, 318–324 (2007).
Shepherd, J.D. & Huganir, R.L. Annu. Rev. Cell Dev. Biol. 23, 613–643 (2007).
Maret, S. et al. Proc. Natl. Acad. Sci. USA 104, 20090–20095 (2007).
Rao, Y. et al. J. Clin. Invest. 117, 4022–4033 (2007).
Sherin, J.E., Shiromani, P.J., McCarley, R.W. & Saper, C.B. Science 271, 216–219 (1996).
About this article
Cite this article
Griffith, L., Rosbash, M. Sleep: hitting the reset button. Nat Neurosci 11, 123–124 (2008). https://doi.org/10.1038/nn0208-123
This article is cited by
Journal of Insect Behavior (2009)