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Storing memories in dendritic channels

An elegant study in this issue shows that induction of synaptic plasticity can also trigger long-lasting increases in dendritic excitability near the potentiated synapses. This may represent a new locus for memory storage and a substrate for metaplasticity.

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Figure 1: Plastic dendrites.


  1. Martin, S.J., Grimwood, P.D. & Morris, R.G. Annu. Rev. Neurosci. 23, 649–711 (2000).

    CAS  Article  Google Scholar 

  2. Frick, A., Magee, J. & Johnston, D. Nat. Neurosci. 7, 126–135 (2004).

    CAS  Article  Google Scholar 

  3. Häusser, M., Spruston, N. & Stuart, G.J. Science 290, 739–744 (2000).

    Article  Google Scholar 

  4. Golding, N.L., Staff, N.P. & Spruston, N. Nature 418, 326–331 (2002).

    CAS  Article  Google Scholar 

  5. Magee, J.C. & Johnston, D. Science 275, 209–213 (1997).

    CAS  Article  Google Scholar 

  6. Johnston, D., Hoffman, D.A., Colbert, C.M. & Magee, J.C. Curr. Opin. Neurobiol. 9, 288–292 (1999).

    CAS  Article  Google Scholar 

  7. Hoffman, D.A., Magee, J.C., Colbert, C.M. & Johnston, D. Nature 387, 869–875 (1997).

    CAS  Article  Google Scholar 

  8. Marder, E., Abbott, L.F., Turrigiano, G.G., Liu, Z. & Golowasch, J. Proc. Natl. Acad. Sci. USA 93, 13481–13486 (1996).

    CAS  Article  Google Scholar 

  9. Bliss, T.V. & Lomo, T. J. Physiol. (Lond.) 232, 331–356 (1973).

    CAS  Article  Google Scholar 

  10. Zhang, W. & Linden, D.J. Nat. Rev. Neurosci. 4, 885–900 (2003).

    CAS  Article  Google Scholar 

  11. Wang, Z., Xu, N.L., Wu, C.P., Duan, S. & Poo, M.M. Neuron 37, 463–472 (2003).

    CAS  Article  Google Scholar 

  12. Ganguly, K., Kiss, L. & Poo, M. Nat. Neurosci. 3, 1018–1026 (2000).

    CAS  Article  Google Scholar 

  13. Yasuda, R., Sabatini, B.L. & Svoboda, K. Nat. Neurosci. 6, 948–955 (2003).

    CAS  Article  Google Scholar 

  14. Poirazi, P. & Mel, B.W. Neuron 29, 779–796 (2001).

    CAS  Article  Google Scholar 

  15. Turrigiano, G.G. & Nelson, S.B. Curr. Opin. Neurobiol. 10, 358–364 (2000).

    CAS  Article  Google Scholar 

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Häusser, M. Storing memories in dendritic channels. Nat Neurosci 7, 98–100 (2004).

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