Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Storing memories in dendritic channels

An elegant study in this issue shows that induction of synaptic plasticity can also trigger long-lasting increases in dendritic excitability near the potentiated synapses. This may represent a new locus for memory storage and a substrate for metaplasticity.

This is a preview of subscription content

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Plastic dendrites.

References

  1. Martin, S.J., Grimwood, P.D. & Morris, R.G. Annu. Rev. Neurosci. 23, 649–711 (2000).

    CAS  Article  Google Scholar 

  2. Frick, A., Magee, J. & Johnston, D. Nat. Neurosci. 7, 126–135 (2004).

    CAS  Article  Google Scholar 

  3. Häusser, M., Spruston, N. & Stuart, G.J. Science 290, 739–744 (2000).

    Article  Google Scholar 

  4. Golding, N.L., Staff, N.P. & Spruston, N. Nature 418, 326–331 (2002).

    CAS  Article  Google Scholar 

  5. Magee, J.C. & Johnston, D. Science 275, 209–213 (1997).

    CAS  Article  Google Scholar 

  6. Johnston, D., Hoffman, D.A., Colbert, C.M. & Magee, J.C. Curr. Opin. Neurobiol. 9, 288–292 (1999).

    CAS  Article  Google Scholar 

  7. Hoffman, D.A., Magee, J.C., Colbert, C.M. & Johnston, D. Nature 387, 869–875 (1997).

    CAS  Article  Google Scholar 

  8. Marder, E., Abbott, L.F., Turrigiano, G.G., Liu, Z. & Golowasch, J. Proc. Natl. Acad. Sci. USA 93, 13481–13486 (1996).

    CAS  Article  Google Scholar 

  9. Bliss, T.V. & Lomo, T. J. Physiol. (Lond.) 232, 331–356 (1973).

    CAS  Article  Google Scholar 

  10. Zhang, W. & Linden, D.J. Nat. Rev. Neurosci. 4, 885–900 (2003).

    CAS  Article  Google Scholar 

  11. Wang, Z., Xu, N.L., Wu, C.P., Duan, S. & Poo, M.M. Neuron 37, 463–472 (2003).

    CAS  Article  Google Scholar 

  12. Ganguly, K., Kiss, L. & Poo, M. Nat. Neurosci. 3, 1018–1026 (2000).

    CAS  Article  Google Scholar 

  13. Yasuda, R., Sabatini, B.L. & Svoboda, K. Nat. Neurosci. 6, 948–955 (2003).

    CAS  Article  Google Scholar 

  14. Poirazi, P. & Mel, B.W. Neuron 29, 779–796 (2001).

    CAS  Article  Google Scholar 

  15. Turrigiano, G.G. & Nelson, S.B. Curr. Opin. Neurobiol. 10, 358–364 (2000).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Häusser, M. Storing memories in dendritic channels. Nat Neurosci 7, 98–100 (2004). https://doi.org/10.1038/nn0204-98

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn0204-98

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing