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Brain calculus: neural integration and persistent activity

Nature Neuroscience volume 4, pages 113–114 (2001)Cite this article

Tank and colleagues make in vivo intracellular recordings from neurons in a 'neural integrator' of the goldfish involved in maintaining eye position. In this circuit, 'working' memory may be the result of persistent changes in the state of the local network.

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Figure 1: Generation of persistent activity through neuronal integration and transient activity through adaptation.

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  1. Section of Neurobiology, Yale University School of Medicine, 333 Cedar Street, New Haven, 06510, Connecticut, USA

    David A. McCormick

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  1. David A. McCormick
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McCormick, D. Brain calculus: neural integration and persistent activity. Nat Neurosci 4, 113–114 (2001). https://doi.org/10.1038/83917

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