The cingulate cortex: divided in pain

The discovery of a circuit from the midcingulate cortex to the posterior insula that is essential for cortical sensitization sheds light on the plasticity mechanisms responsible for the transition from acute to chronic pain.

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Figure 1: Cortical sensitization gates sensory hypersensitivity.

Debbie Maizels / Springer Nature

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Correspondence to Thomas Nevian.

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Nevian, T. The cingulate cortex: divided in pain. Nat Neurosci 20, 1515–1517 (2017). https://doi.org/10.1038/nn.4664

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