Supplementary Figure 5: Splenectomy did not reverse SCI-induced immune cell depletion. | Nature Neuroscience

Supplementary Figure 5: Splenectomy did not reverse SCI-induced immune cell depletion.

From: Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex

Supplementary Figure 5

In contrast to surgical removal of the adrenals, removal of the spleen which is similarly innervated by sympathetic fibers via the splanchnic nerve, could not re-establish the SCI-induced cell death in thymus and lymph nodes (a) and did not change the characteristic SCI-induced pattern of B cell populations in the bone marrow (b-e) with massive enrichment of mature B cells (e).

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