Supplementary Figure 3: Sciatic nerve lesion has no effect on immune cell composition of the innervated bone marrow. | Nature Neuroscience

Supplementary Figure 3: Sciatic nerve lesion has no effect on immune cell composition of the innervated bone marrow.

From: Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex

Supplementary Figure 3

(a) Deafferentiation of the tibial bone marrow by right sciatic nerve injury (compared to sham) did not change the total number of bone marrow cells. (b-d) Right sciatic nerve lesion did not change the number and frequency of CD19+ (b), CD4+ (c), CD8+ (d), Gr-1+, NK1.1+, CD11c+, and CD11b+ cells (not shown) in the ipsi- and contralateral bone marrow. (e-f) Homing of donor splenocytes for 2 hours (e) as well as redistribution for 15 hours (f) to the bone marrow was equal in mice with right sciatic nerve lesion and sham-operated animals. Data are mean ± SEM, n=6-9 animals per group. * p<0.05; 1-way ANOVA with Tukey’s multiple comparison test.

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