A neuronal mechanism for recall of bad events

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Hippocampal place cells are traditionally thought to represent locations where animals currently are or predict where they are headed. However, new results reveal that place cells also represent distant places that are actively avoided.

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Figure 1: Awake replay during sharp wave-ripples (SWRs) supports recall of fear memory.

References

  1. 1

    Wu, C., Haggerty, D., Kemere, C. & Ji, D. Nat. Neurosci. 20, 571–580 (2017).

  2. 2

    Buzsáki, G. Brain Res. 398, 242–252 (1986).

  3. 3

    Lee, A.K. & Wilson, M.A. Neuron 36, 1183–1194 (2002).

  4. 4

    Pfeiffer, B.E. & Foster, D.J. Nature 497, 74–79 (2013).

  5. 5

    Singer, A.C., Carr, M.F., Karlsson, M.P. & Frank, L.M. Neuron 77, 1163–1173 (2013).

  6. 6

    Jadhav, S.P., Kemere, C., German, P.W. & Frank, L.M. Science 336, 1454–1458 (2012).

  7. 7

    Brun, V.H. et al. Science 296, 2243–2246 (2002).

  8. 8

    Nakazawa, K. et al. Science 297, 211–218 (2002).

  9. 9

    Colgin, L.L. et al. Nature 462, 353–357 (2009).

  10. 10

    Carr, M.F., Karlsson, M.P. & Frank, L.M. Neuron 75, 700–713 (2012).

  11. 11

    Pfeiffer, B.E. & Foster, D.J. Science 349, 180–183 (2015).

  12. 12

    Bieri, K.W., Bobbitt, K.N. & Colgin, L.L. Neuron 82, 670–681 (2014).

  13. 13

    Zheng, C., Bieri, K.W., Hsiao, Y.T. & Colgin, L.L. Neuron 89, 398–408 (2016).

  14. 14

    Foster, D.J. & Wilson, M.A. Hippocampus 17, 1093–1099 (2007).

  15. 15

    Gupta, A.S., van der Meer, M.A., Touretzky, D.S. & Redish, A.D. Neuron 65, 695–705 (2010).

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Correspondence to Chenguang Zheng or Laura Lee Colgin.

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The authors declare no competing financial interests.

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Zheng, C., Colgin, L. A neuronal mechanism for recall of bad events. Nat Neurosci 20, 501–503 (2017) doi:10.1038/nn.4525

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