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Pass the salt: the central control of sodium intake

Nature Neuroscience volume 20, pages 130–131 (2017)Cite this article

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The biological drive to consume salt ensures that we consume adequate sodium for survival. In this issue of Nature Neuroscience, two articles provide insight into the neurons and circuits that regulate sodium appetite.

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Figure 1: Neural circuits involved in osmoregulation.

Debbie Maizels / Springer Nature

References

  1. Geerling, J.C. & Loewy, A.D. Exp. Physiol. 93, 177–209 (2008).

    Article  CAS  Google Scholar 

  2. Richter, C.F. Am. J. Physiol. 115, 155–161 (1936).

    Article  CAS  Google Scholar 

  3. McEwen, B.S., Lambdin, L.T., Rainbow, T.C. & De Nicola, A.F. Neuroendocrinology 43, 38–43 (1986).

    Article  CAS  Google Scholar 

  4. Buggy, J. & Fisher, A.E. Nature 250, 733–735 (1974).

    Article  CAS  Google Scholar 

  5. Jarvie, B.C. & Palmiter, R.D. Nat. Neurosci. 20, 167–169 (2017).

    Article  CAS  Google Scholar 

  6. Matsuda, T. et al. Nat. Neurosci. 20, 230–241 (2017).

    Article  CAS  Google Scholar 

  7. Formenti, S. et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 304, R252–R259 (2013).

    Article  CAS  Google Scholar 

  8. Geerling, J.C., Engeland, W.C., Kawata, M. & Loewy, A.D. J. Neurosci. 26, 411–417 (2006).

    Article  CAS  Google Scholar 

  9. Geerling, J.C. & Loewy, A.D. J. Comp. Neurol. 497, 223–250 (2006).

    Article  CAS  Google Scholar 

  10. Oka, Y., Ye, M. & Zuker, C.S. Nature 520, 349–352 (2015).

    Article  CAS  Google Scholar 

  11. Johnson, R.F., Beltz, T.G., Thunhorst, R.L. & Johnson, A.K. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285, R394–R403 (2003).

    Article  CAS  Google Scholar 

  12. Nation, H.L., Nicoleau, M., Kinsman, B.J., Browning, K.N. & Stocker, S.D. J. Neurophysiol. 115, 3123–3129 (2016).

    Article  CAS  Google Scholar 

  13. Betley, J.N. et al. Nature 521, 180–185 (2015).

    Article  CAS  Google Scholar 

  14. Betley, J.N., Cao, Z.F., Ritola, K.D. & Sternson, S.M. Cell 155, 1337–1350 (2013).

    Article  CAS  Google Scholar 

  15. Grill, H.J. Obesity (Silver Spring) 14 (Suppl. 5), 216S–221S (2006).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Amber L. Alhadeff and J. Nicholas Betley are in the Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.,

    Amber L Alhadeff & J Nicholas Betley

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  1. Amber L Alhadeff
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  2. J Nicholas Betley
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Correspondence to J Nicholas Betley.

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Alhadeff, A., Betley, J. Pass the salt: the central control of sodium intake. Nat Neurosci 20, 130–131 (2017). https://doi.org/10.1038/nn.4485

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