Supplementary Figure 3: Unilateral blockade of vibrissa motor cortex (by AMPA & NMDA antagonists) increases contralateral whisker movement and protraction | Nature Neuroscience

Supplementary Figure 3: Unilateral blockade of vibrissa motor cortex (by AMPA & NMDA antagonists) increases contralateral whisker movement and protraction

From: Vibrissa motor cortex activity suppresses contralateral whisking behavior

Supplementary Figure 3

(a)Example image of anaesthetized rat after unilateral VMC blockade (right hemisphere) by superfusion of APV (an NMDA antagonist) and NBQX (an AMPA antagonist).

(b)Example ipsilateral (blue) and contralateral (red) whisking traces of whisker micromovements, which escape light anaesthesia (Whisker arc 1). The contralateral whiskers are more protracted (~27° vs. ~32°) and the contralateral micromovements have a larger amplitude.

(c)After VMC blockade, the whisker set point is higher contralaterally (red markers) than ipsilaterally (blue markers) to the blocked hemisphere (N = 3 rats).

(d)After VMC blockade, the whisking power is much higher (~5 fold) in the contralateral whiskers than in the ipsilateral whiskers (Markers indicate ratio of contralateral to ipsilateral whisker power).

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