Supplementary Figure 11: Cholinergic control of inhibition during context-switching | Nature Neuroscience

Supplementary Figure 11: Cholinergic control of inhibition during context-switching

From: Parallel processing by cortical inhibition enables context-dependent behavior

Supplementary Figure 11

a, Example neuron in saline showing that the time lag between excitation and inhibition is smaller in the active context relative to the time lag in the passive context (ΔE-I time lag: ‒3.6 ms, i.e., inhibition and excitation are 3.6 ms closer together in the active context). b, Example neuron in atropine showing an increase in the time lag between excitation and inhibition (ΔE-I time lag: 20.5 ms). c, Summary of the change in time lag of synaptic inputs in the control and atropine conditions (saline: n=12 neurons, ΔE-I time lag ‒4.4±2.2 ms; atropine: n=7 neurons, ΔE-I time lag 17.0±5.7 ms, p<0.05, Student’s paired two-tailed t-test).

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