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Brains, genes and power

Nature Neuroscience volume 19, pages 1428–1430 (2016)Cite this article

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Gene expression data from more than 500 human brains shed light on the molecular consequences of genetic variation that contributes to schizophrenia.

Schizophrenia is a neuropsychiatric disorder that afflicts up to 1% of humans and affects diverse brain functions, including perception, emotion and cognition. Despite extensive characterization of the electrophysiological, cell morphological and molecular alterations accompanying the disease, effective treatment remains elusive. This is, in part, because our understanding of the causes of schizophrenia are incomplete.

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Figure 1: Brain gene expression in schizophrenia.

Marina Corral Spence/Nature Publishing Group

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Authors and Affiliations

  1. Frank W. Albert is in the Department of Genetics, Cell Biology & Development, University of Minnesota, Minneapolis, Minnesota, USA.,

    Frank W Albert

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  1. Frank W Albert
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Correspondence to Frank W Albert.

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The author declares no competing financial interests.

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Albert, F. Brains, genes and power. Nat Neurosci 19, 1428–1430 (2016). https://doi.org/10.1038/nn.4424

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