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Brains, genes and power

Nature Neuroscience volume 19, pages 1428–1430 (2016)Cite this article

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Gene expression data from more than 500 human brains shed light on the molecular consequences of genetic variation that contributes to schizophrenia.

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Figure 1: Brain gene expression in schizophrenia.

Marina Corral Spence/Nature Publishing Group

References

  1. Sullivan, P.F., Kendler, K.S. & Neale, M.C. Arch. Gen. Psychiatry 60, 1187–1192 (2003).

    Article  PubMed  Google Scholar 

  2. Fromer, M. et al. Nat. Neurosci. 19, 1442–1453 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Nature 511, 421–427 (2014).

  4. Loh, P.-R. et al. Nat. Genet. 47, 1385–1392 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Albert, F.W. & Kruglyak, L. Nat. Rev. Genet. 16, 197–212 (2015).

    Article  CAS  PubMed  Google Scholar 

  6. Brem, R.B., Yvert, G., Clinton, R. & Kruglyak, L. Science 296, 752–755 (2002).

    Article  CAS  PubMed  Google Scholar 

  7. Gusev, A. et al. Am. J. Hum. Genet. 95, 535–552 (2014).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Albert, F.W., Treusch, S., Shockley, A.H., Bloom, J.S. & Kruglyak, L. Nature 506, 494–497 (2014).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Aguet, F. et al. Local genetic effects on gene expression across 44 human tissues. Preprint at bioRxiv http://dx.doi.org/10.1101/074450 (2016).

  10. He, X. et al. Am. J. Hum. Genet. 92, 667–680 (2013).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Gusev, A. et al. Nat. Genet. 48, 245–252 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Gamazon, E.R. et al. Nat. Genet. 47, 1091–1098 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Button, K.S. et al. Nat. Rev. Neurosci. 14, 365–376 (2013).

    Article  CAS  PubMed  Google Scholar 

  14. Robinson, E.B. et al. Nat. Genet. 48, 552–555 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Keren, L. et al. Cell 166, 1282–1294.e18 (2016).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Frank W. Albert is in the Department of Genetics, Cell Biology & Development, University of Minnesota, Minneapolis, Minnesota, USA.,

    Frank W Albert

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  1. Frank W Albert
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Correspondence to Frank W Albert.

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The author declares no competing financial interests.

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Albert, F. Brains, genes and power. Nat Neurosci 19, 1428–1430 (2016). https://doi.org/10.1038/nn.4424

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