Abstract
At this unique and exciting time for psychiatry, novel therapies for individuals with mental illnesses seem just around the corner. In particular, recent technological advancements in the study of neural circuits provide reasons to be optimistic that the field is headed in the right direction. Nonetheless, maximizing the chances of translating these advancements into real improvements in patient care requires a carefully considered road map.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Lost in translation: no effect of repeated optogenetic cortico-striatal stimulation on compulsivity in rats
Translational Psychiatry Open Access 24 May 2021
-
Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
Nature Communications Open Access 01 October 2020
-
Neuregulin 1: an intriguing therapeutic target for neurodevelopmental disorders
Translational Psychiatry Open Access 16 June 2020
Access options
Subscribe to Journal
Get full journal access for 1 year
$79.00
only $6.58 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Tax calculation will be finalised during checkout.
Buy article
Get time limited or full article access on ReadCube.
$32.00
All prices are NET prices.
References
LeDoux, J. Curr. Biol. 17, R868–R874 (2007).
Fanselow, M.S. & Gale, G.D. Ann. NY Acad. Sci. 985, 125–134 (2003).
Davis, M. Int. Rev. Neurobiol. 36, 225–266 (1994).
Morrison, S.E. & Salzman, C.D. Curr. Opin. Neurobiol. 20, 221–230 (2010).
Gallagher, M. & Schoenbaum, G. Ann. NY Acad. Sci. 877, 397–411 (1999).
Paton, J.J., Belova, M.A., Morrison, S.E. & Salzman, C.D. Nature 439, 865–870 (2006).
Namburi, P. et al. Nature 520, 675–678 (2015).
Beyeler, A. et al. Neuron 90, 348–361 (2016).
Gore, F. et al. Cell 162, 134–145 (2015).
Miller, G. Science 314, 1674–1676 (2006).
Rakoczy, E.P. et al. Lancet 386, 2395–2403 (2015).
Kelly, M.J., O'Keeffe, G.W. & Sullivan, A.M. Expert Rev. Mol. Med. 17, e8 (2015).
Pleticha, J., Maus, T.P. & Beutler, A.S. Mayo Clin. Proc. 91, 522–533 (2016).
Jennings, C.G. et al. Nat. Neurosci. 19, 1123–1130 (2016).
Spellman, T. et al. Nature 522, 309–314 (2015).
Tamura, M., Mukai, J., Gordon, J.A. & Gogos, J.A. Neuron 89, 1100–1109 (2016).
Wells, M.F., Wimmer, R.D., Schmitt, L.I., Feng, G. & Halassa, M.M. Nature 532, 58–63 (2016).
Lozano, A.M. & Lipsman, N. Neuron 77, 406–424 (2013).
Chervyakov, A.V., Chernyavsky, A.Y., Sinitsyn, D.O. & Piradov, M.A. Front. Hum. Neurosci. 9, 303 (2015).
Sullivan, P.F., Daly, M.J. & O'Donovan, M. Nat. Rev. Genet. 13, 537–551 (2012).
Estes, M.L. & McAllister, A.K. Science 353, 772–777 (2016).
Nemeroff, C.B. Neuron 89, 892–909 (2016).
Heckenast, J.R., Wilkinson, L.S. & Jones, M.W. Adv. Genet. 92, 75–106 (2015).
Glasser, M.F. et al. Nat. Neurosci. 19, 1175–1187 (2016).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Gordon, J. On being a circuit psychiatrist. Nat Neurosci 19, 1385–1386 (2016). https://doi.org/10.1038/nn.4419
Published:
Issue Date:
DOI: https://doi.org/10.1038/nn.4419
This article is cited by
-
Lost in translation: no effect of repeated optogenetic cortico-striatal stimulation on compulsivity in rats
Translational Psychiatry (2021)
-
Closed-loop enhancement and neural decoding of cognitive control in humans
Nature Biomedical Engineering (2021)
-
Neuregulin 1: an intriguing therapeutic target for neurodevelopmental disorders
Translational Psychiatry (2020)
-
The symptom network structure of depressive symptoms in late-life: Results from a European population study
Molecular Psychiatry (2020)
-
Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
Nature Communications (2020)