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Neocortex: a lean mean memory storage machine

Connectivity patterns of neocortex exhibit several odd properties: for example, most neighboring excitatory neurons do not connect, which seems curiously wasteful. Brunel's elegant theoretical treatment reveals how optimal information storage can naturally impose these peculiar properties.

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Figure 1: Memory storage in recurrently connected neural networks is optimal when most synaptic strengths are zero.

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Correspondence to P Jesper Sjöström.

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Mizusaki, B., Stepanyants, A., Chklovskii, D. et al. Neocortex: a lean mean memory storage machine. Nat Neurosci 19, 643–644 (2016). https://doi.org/10.1038/nn.4292

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