Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

And the beat goes on: from clock to behavior

Master circadian clocks in discrete neurons trigger profound daily changes in brain states, such as sleep and wake states. A study now finds a circuit through which these pacemakers act to control daily behavioral rhythms in Drosophila.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The Drosophila clock networks driving circadian behavior.

References

  1. Panda, S., Hogenesch, J.B. & Kay, S.A. Nature 417, 329–335 (2002).

    Article  CAS  Google Scholar 

  2. Cavey, M., C.B., Bertet, C. & Nat. Neurosci. 19, 587–595 (2016).

    Article  CAS  Google Scholar 

  3. Al-Anzi, B. et al. Curr. Biol. 20, 969–978 (2010).

    Article  CAS  Google Scholar 

  4. de Haro, M. et al. Cell Tissue Res. 339, 321–336 (2010).

    Article  Google Scholar 

  5. Peschel, N. & Helfrich-Forster, C. FEBS Lett. 585, 1435–1442 (2011).

    Article  CAS  Google Scholar 

  6. Lima, S.Q. & Miesenbock, G. Cell 121, 141–152 (2005).

    Article  CAS  Google Scholar 

  7. Pulver, S.R., Pashkovski, S.L., Hornstein, N.J., Garrity, P.A. & Griffith, L.C. J. Neurophysiol. 101, 3075–3088 (2009).

    Article  Google Scholar 

  8. Kitamoto, T. J. Neurobiol. 47, 81–92 (2001).

    Article  CAS  Google Scholar 

  9. Cavanaugh, D.J. et al. Cell 157, 689–701 (2014).

    Article  CAS  Google Scholar 

  10. Cao, G. et al. Cell 154, 904–913 (2013).

    Article  CAS  Google Scholar 

  11. Gong, Y. et al. Science 350, 1361–1366 (2015).

    Article  CAS  Google Scholar 

  12. Pirez, N., Christmann, B.L. & Griffith, L.C. J. Neurophysiol 110, 700–708 (2013).

    Article  CAS  Google Scholar 

  13. Kunst, M. et al. Curr. Biol. 24, 2652–2664 (2014).

    Article  CAS  Google Scholar 

  14. Luo, W. & Sehgal, A. Cell 148, 765–779 (2012).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ravi Allada.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Flourakis, M., Allada, R. And the beat goes on: from clock to behavior. Nat Neurosci 19, 529–530 (2016). https://doi.org/10.1038/nn.4278

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn.4278

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing