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Hippogate: a break-in from entorhinal cortex

Discrimination of neutral from harmful environments is important for survival. But how do salient contextual signals yield persisting memories? A study uncovers a circuit that increases the specificity of hippocampus-based memories.

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Figure 1: Functional organization of the LEC-hippocampus circuit.

Katie Vicari/Nature Publishing Group

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Correspondence to Allyson Alexander or Ivan Soltesz.

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Alexander, A., Soltesz, I. Hippogate: a break-in from entorhinal cortex. Nat Neurosci 19, 530–532 (2016). https://doi.org/10.1038/nn.4253

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