Supplementary Figure 9: Nerve injury and CSF1-induced microglia proliferation in the dorsal horn is DAP12-independent. | Nature Neuroscience

Supplementary Figure 9: Nerve injury and CSF1-induced microglia proliferation in the dorsal horn is DAP12-independent.

From: Injured sensory neuron–derived CSF1 induces microglial proliferation and DAP12-dependent pain

Supplementary Figure 9

(a) Advillin-Cre-mediated deletion of Csf1 from sensory neurons decreases nerve injury-induced dorsal horn microglia proliferation (3 d post injury; 3 mice per group); (b) Microglial proliferation 3 d post injury persists in Tyrobp–/– mice (3 d post injury, n = 4 mice); (c) Dorsal horn microglia proliferation after intrathecal CSF1 (3 d); (d) Intrathecal CSF1-induced microglia proliferation persists in Tyrobp–/– mice. Scale bar represents 100 μm.

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