Supplementary Figure 9 : Fetal brain mQTLs ar1e significantly enriched for schizophrenia genetic risk variants.

From: Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

Supplementary Figure 9

Different significance thresholds (represented by different colored bars) were used to classify SNP associations from a recent large GWAS analysis of schizophrenia1. There is an enrichment of schizophrenia-associated variants amongst fetal brain mQTLs at all tested GWAS significance thresholds. Shown is the enrichment fold-change with 95% confidence intervals based on 1 million simulated SNP-sets. See also Table 1.

1. Schizophrenia Working Group of the Psychiatric Genomics Consortium,. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511, 421-427 (2014).