Supplementary Figure 8 : The overlap between independent fetal brain mQTL signals with the sentinelized subsignals from a brain eQTL dataset.

From: Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

Supplementary Figure 8

Histogram of overlap between simulated mQTL SNPs set (n = 1,000,000 simulations, matched for allele frequency) with the sentinelized eQTL set published by Ramasamy et al.. The vertical red line represents the true overlap, which is greater than any of the simulations (fold change = 4.23, P < 1.00x10−6 after 1 million simulations).

1. Ramasamy, A. et al. Genetic variability in the regulation of gene expression in ten regions of the human brain. Nat Neurosci 17, 1418-28 (2014).