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From phenotypic chaos to neurobiological order

Complex demographic and behavioral phenotypes can arise from coordinated interactions among brain systems. A single axis of co-variation spanning 'negative' and 'positive' attributes links diverse participant characteristics with specific patterns of brain connectivity.

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Figure 1: A single positive-negative mode of covariation links diverse demographic and behavioral phenotypes with the collective set of functional connections in the human brain.


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Correspondence to Avram J Holmes or B T Thomas Yeo.

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Holmes, A., Yeo, B. From phenotypic chaos to neurobiological order. Nat Neurosci 18, 1532–1534 (2015).

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