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GABA receptors in a state of fear

Nature Neuroscience volume 18, pages 1194–1196 (2015)Cite this article

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Our internal states can color our memories just as powerfully as the external environment. A study finds that hippocampal GABAA receptors and associated microRNAs are important for generating state-dependent contextual fear memories.

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Figure 1: Activating hippocampal GABAA receptors generates a state-dependent contextual fear memory.

Kim Caesar/Nature Publishing Group

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Authors and Affiliations

  1. Andrew Holmes is at the Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, US National Institutes of Health, Bethesda, Maryland, USA, and,

    Andrew Holmes

  2. Department of Neurobiology, and the Department of Stress Neurobiology and Neurogenetics, Alon Chen is at the Ruhman Family Laboratory for Research on the Neurobiology of Stress, Weizmann Institute of Science, Rehovot, Israel, Max Planck Institute of Psychiatry, Munich, Germany.,

    Alon Chen

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  1. Andrew Holmes
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  2. Alon Chen
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Correspondence to Andrew Holmes.

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The authors declare no competing financial interests.

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Holmes, A., Chen, A. GABA receptors in a state of fear. Nat Neurosci 18, 1194–1196 (2015). https://doi.org/10.1038/nn.4098

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