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Sex, drugs and pain control

Nature Neuroscience volume 18, pages 10591060 (2015) | Download Citation

A study finds that pain hypersensitivity in male and female mice is differentially dependent on microglia and T cells, and describes a sex-specific response to microglia-targeted pain treatments. This sex difference will be important to consider when developing treatments for pain and other neurological disorders involving microglia and immune cells.

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Author information

Affiliations

  1. Victoria E. Brings and Mark J. Zylka are in the Department of Cell Biology and Physiology, UNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

    • Victoria E Brings
    •  & Mark J Zylka

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Mark J Zylka.

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DOI

https://doi.org/10.1038/nn.4057

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