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Attention alters orientation processing in the human lateral geniculate nucleus

Nature Neuroscience volume 18, pages 496498 (2015) | Download Citation

Abstract

Orientation selectivity is a cornerstone property of vision, commonly believed to emerge in the primary visual cortex. We found that reliable orientation information could be detected even earlier, in the human lateral geniculate nucleus, and that attentional feedback selectively altered these orientation responses. This attentional modulation may allow the visual system to modify incoming feature-specific signals at the earliest possible processing site.

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Acknowledgements

We thank V. Casagrande, J. Schall and R. Blake for valuable comments and discussion. This work was supported by US National Institutes of Health grant R01 EY017082 to F.T., R01 EB000461 (J. Gore, Vanderbilt University), and US National Institutes of Health Fellowship F32-EY022569 to M.S.P.

Author information

Affiliations

  1. Department of Psychological and Brain Sciences, and the Center for Computational Neuroscience and Neural Technology, Boston University, Boston, Massachusetts, USA.

    • Sam Ling
  2. Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands.

    • Sam Ling
  3. Department of Psychology and the Vanderbilt Vision Research Center, Vanderbilt University, Nashville, Tennessee, USA.

    • Michael S Pratte
    •  & Frank Tong

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Contributions

S.L., M.S.P. and F.T. conceived and designed the experiments. S.L. and M.S.P. collected the data. S.L. conducted the data analyses. S.L., M.S.P. and F.T. wrote the manuscript.

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Sam Ling.

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DOI

https://doi.org/10.1038/nn.3967

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