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Pain and the PAG: learning from painful mistakes

Jeremy Bentham distilled animal behavior as avoiding pain and seeking pleasure. Now, using a combination of different methodological approaches, Roy et al. identify a neural mechanism relevant for learning to avoid pain.

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Figure 1: Main experimental findings and potential new directions for study.


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Correspondence to Irene Tracey.

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The authors declare no competing financial interests.

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Eippert, F., Tracey, I. Pain and the PAG: learning from painful mistakes. Nat Neurosci 17, 1438–1439 (2014).

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