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A selector orchestrates cortical function

Molecular orchestration mediated by Fezf2, a master transcriptional regulator of a particular type of cortical neurons, directly determines both their identity and axonal routing, and thus their connectivity.

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Figure 1: Fezf2 regulates a large number of genes to govern the acquisition of CSMN-specific identity.

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Correspondence to Toshihide Yamashita.

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Ueno, M., Fujiki, R. & Yamashita, T. A selector orchestrates cortical function. Nat Neurosci 17, 1016–1017 (2014). https://doi.org/10.1038/nn.3765

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