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The needle in the haystack

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Spike-based approaches to feature selectivity in sensory pathways can bias toward only the most active neurons. A subthreshold method identifies feature selectivity in the rodent vibrissal system regardless of spiking activity.

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Figure 1: Identifying feature selectivity.

Debbie Maizels/Nature Publishing Group

References

  1. Hubel, D.H. & Wiesel, T. J. Physiol. (Lond.) 160, 106–154 (1962).

    Article  CAS  Google Scholar 

  2. Ramirez, A. et al. Nat. Neurosci. 17, 866–875 (2014).

    Article  CAS  Google Scholar 

  3. Jones, J.P. & Palmer, L.A. J. Neurophysiol. 58, 1187–1211 (1987).

    Article  CAS  Google Scholar 

  4. Maravall, M., Petersen, R.S., Fairhall, A.L., Arabzadeh, E. & Diamond, M.E. PLoS Biol. 5, e19 (2007).

    Article  Google Scholar 

  5. Estebanez, L., El Boustani, S., Destexhe, A. & Shulz, D.E. Nat. Neurosci. 15, 1691–1699 (2012).

    Article  CAS  Google Scholar 

  6. Bensmaia, S.J., Denchev, P.V., Dammann, J.F., Craig, J.C. & Hsiao, S.S. J. Neurosci. 28, 776–786 (2008).

    Article  CAS  Google Scholar 

  7. Barth, A.L. & Poulet, J.F.a. Trends Neurosci. 35, 345–355 (2012).

    Article  CAS  Google Scholar 

  8. Wang, Q., Webber, R.M. & Stanley, G.B. Nat. Neurosci. 13, 1534–1541 (2010).

    Article  CAS  Google Scholar 

  9. Ollerenshaw, D.R., Zheng, H.J.V.V., Millard, D.C., Wang, Q. & Stanley, G.B. Neuron 81, 1152–1164 (2014).

    Article  CAS  Google Scholar 

  10. Niell, C.M. & Stryker, M.P. Neuron 65, 472–479 (2010).

    Article  CAS  Google Scholar 

  11. Keller, G.B., Bonhoeffer, T. & Hübener, M. Neuron 74, 809–815 (2012).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Garrett B Stanley.

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Shephard, C., Stanley, G. The needle in the haystack. Nat Neurosci 17, 752–753 (2014). https://doi.org/10.1038/nn.3730

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