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Inhaling: endocannabinoids and food intake

Feeding effects of CB1 receptors are commonly associated with exogenous cannabinoids, but a study now identifies a circuit by which endocannabinoid activation of CB1 receptors in the main olfactory bulb regulates normal food intake.

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Figure 1: Metabolic state modulates feeding behaviors via cannabinoid activity in the main olfactory bulb (MOB).

Katie Vicari

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Correspondence to Jaime G Maldonado-Avilés or Ralph J DiLeone.

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Maldonado-Avilés, J., DiLeone, R. Inhaling: endocannabinoids and food intake. Nat Neurosci 17, 336–337 (2014). https://doi.org/10.1038/nn.3653

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