High-grade glioblastomas survive glucose-poor environments by becoming more stem cell–like. Increased glucose uptake by the transporter Glut3, a new biomarker of poor clinical outcome, drives this enhanced malignant progression.
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Ilkhanizadeh, S., Weiss, W. Starvation favors glioma stem cells. Nat Neurosci 16, 1359–1361 (2013). https://doi.org/10.1038/nn.3524
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DOI: https://doi.org/10.1038/nn.3524
