A finely tuned cortical amplifier

Three studies in visual and auditory cortex show that intracortical excitatory inputs amplify incoming sensory signals, as their sensory tuning is closely matched to that arriving from the sensory thalamus.

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Figure 1: Dissecting the contributions of thalamocortical and intracortical excitation to total excitation in layer 4 neurons in mouse visual cortex.

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Correspondence to Thomas Mrsic-Flogel.

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Han, Y., Mrsic-Flogel, T. A finely tuned cortical amplifier. Nat Neurosci 16, 1166–1168 (2013) doi:10.1038/nn.3507

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