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Drinking through the pain


A feature of abusive alcohol drinking has been modeled successfully in experiments with rats. The experiments show that changes in NMDA signaling in specific neural circuits accompany the transition to aversion-resistant drinking.

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Figure 1: Neural circuitry underlying aversion-insensitive alcohol consumption.

Katie Vicari


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Correspondence to Thomas L Kash or John C Crabbe.

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The authors declare no competing financial interests.

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Kash, T., Crabbe, J. Drinking through the pain. Nat Neurosci 16, 987–988 (2013).

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