A feature of abusive alcohol drinking has been modeled successfully in experiments with rats. The experiments show that changes in NMDA signaling in specific neural circuits accompany the transition to aversion-resistant drinking.
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The authors declare no competing financial interests.
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Kash, T., Crabbe, J. Drinking through the pain. Nat Neurosci 16, 987–988 (2013). https://doi.org/10.1038/nn.3476