News & Views | Published:

Brain-wide gain modulation: the rich get richer

Nature Neuroscience volume 16, pages 989990 (2013) | Download Citation

A study now shows how brain-wide gain modulation, indexed by pupil diameter, shapes the structure of brain-wide neural interactions and, consequently, trial-and-error learning.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , & Science 249, 892–895 (1990).

  2. 2.

    & Annu. Rev. Neurosci. 28, 403–450 (2005).

  3. 3.

    & Exp. Neurol. 67, 11–34 (1980).

  4. 4.

    & Nat. Rev. Neurosci. 10, 186–198 (2009).

  5. 5.

    , & Nat. Rev. Neurosci. 13, 121–134 (2012).

  6. 6.

    , & Nat. Neurosci. 16, 1146–1153 (2013).

  7. 7.

    & J. Cogn. Neurosci. 23, 1587–1596 (2011).

  8. 8.

    , , & Cogn. Affect. Behav. Neurosci. 10, 252–269 (2010).

  9. 9.

    & Science 154, 1583–1585 (1966).

  10. 10.

    Nature 453, 869–878 (2008).

  11. 11.

    , & Nat. Rev. Neurosci. 10, 383–390 (2009).

  12. 12.

    et al. Nat. Neurosci. 15, 1040–1046 (2012).

  13. 13.

    et al. Science 334, 1151–1153 (2011).

  14. 14.

    , , & J. Neurosci. 30, 8190–8196 (2010).

Download references

Author information

Affiliations

  1. Tobias H. Donner is in the Department of Psychology and Cognitive Science Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands

    • Tobias H Donner
  2. Sander Nieuwenhuis is at the Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.

    • Sander Nieuwenhuis

Authors

  1. Search for Tobias H Donner in:

  2. Search for Sander Nieuwenhuis in:

Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Tobias H Donner or Sander Nieuwenhuis.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nn.3471

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing