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Itching for relief

Little is known about the molecular and cellular mechanisms underlying acute and chronic itch. A new technique for silencing peripheral itch neurons defines two independent itch circuits that transmit signals to the CNS.

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Figure 1: QX-314–mediated inhibition of itch-sensitive peripheral somatosensory neurons.

Katie Vicari

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Correspondence to Diana Bautista.

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Wilson, S., Bautista, D. Itching for relief. Nat Neurosci 16, 775–777 (2013). https://doi.org/10.1038/nn.3442

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