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Learning to deal with life's ups and downs

A study shows that circadian glucocorticoid oscillations have dual roles in dendritic spine plasticity, controlling spine formation and elimination through distinct mechanisms important for motor learning.

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Figure 1: Two-photon in vivo imaging of the mouse motor cortex before and after motor learning on the rotarod task.

Marina Corral Spence

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Correspondence to Scott J Russo.

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Heshmati, M., Russo, S. Learning to deal with life's ups and downs. Nat Neurosci 16, 658–659 (2013). https://doi.org/10.1038/nn.3400

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