A study reconciling contradictory in vitro and in vivo data on neuroligins in synapse formation shows that cell-to-cell variability in neuroligin-1 levels, mediating competition for presynaptic inputs, regulates synapse density.
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Barrow, S., McAllister, A. Neuroligins help dendrites keep up with the Joneses. Nat Neurosci 15, 1609–1611 (2012). https://doi.org/10.1038/nn.3271
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DOI: https://doi.org/10.1038/nn.3271
