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Reward and punishment illuminated

How do outcomes affect future behavior? A study using precise optogenetic stimulation finds that learning from positive reinforcement is mediated by striatal pathways distinct from those that mediate learning from punishment.

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Figure 1: Simplified schematic of basal ganglia anatomy and circuit response to optogenetic stimulation.


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Correspondence to Kenway Louie.

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Paton, J., Louie, K. Reward and punishment illuminated. Nat Neurosci 15, 807–809 (2012).

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