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Astrocytes join the plasticity party

Nature Neuroscience volume 15, pages 649–651 (2012)Cite this article

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In the developing cortex, spike timing–dependent long-term depression requires cannabinoid-induced glutamate release from astrocytes. Astrocytes may be integral to the coincidence detection that guides plasticity and map formation.

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Figure 1: Astrocyte cannabinoid and glutamate signaling triggers tLTD at developing somatosensory cortical synapses.

Katie Vicari

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Authors and Affiliations

  1. David J. Rossi is in the Department of Behavioral Neuroscience at Oregon Health & Science University, Portland, Oregon, USA.,

    David J Rossi

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  1. David J Rossi
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Correspondence to David J Rossi.

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The author declares no competing financial interests.

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Rossi, D. Astrocytes join the plasticity party. Nat Neurosci 15, 649–651 (2012). https://doi.org/10.1038/nn.3095

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