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Vision and olfaction say UNC-le to G proteins

Nature Neuroscience volume 14, pages 805–806 (2011)Cite this article

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Guided by novel structural insights, a study now demonstrates that UNC119 is a lipid-binding protein essential for proper trafficking of G-protein a subunits in mammalian photoreceptors and Caenorhabditis elegans sensory neurons.

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Figure 1: The proposed role of UNC119 in transducin trafficking.

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Authors and Affiliations

  1. Eyal Vardy and Bryan L. Roth are in the Departments of Pharmacology and Medicinal Chemistry and the Program in Neurosciences, University of North Carolina Chapel Hill Medical School, Chapel Hill, North Carolina, USA.,

    Eyal Vardy & Bryan L Roth

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  1. Eyal Vardy
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  2. Bryan L Roth
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Correspondence to Bryan L Roth.

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The authors declare no competing financial interests.

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Vardy, E., Roth, B. Vision and olfaction say UNC-le to G proteins. Nat Neurosci 14, 805–806 (2011). https://doi.org/10.1038/nn.2863

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