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Craving, context and the cortex

A new study challenges the idea that the ventromedial prefrontal cortex inhibits drug relapse, by selectively inactivating a subpopulation of neurons in this brain area and showing attenuation of context-induced reinstatement of heroin seeking.

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Figure 1: Cortical neuronal ensembles underlying context-induced reinstatement of drug seeking.

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Correspondence to Olivier George or George F Koob.

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George, O., Koob, G. Craving, context and the cortex. Nat Neurosci 14, 409–410 (2011). https://doi.org/10.1038/nn.2787

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