Tailored health interventions can be more effective in eliciting positive behavior change than generic interventions, but the underlying neural mechanisms are not yet understood. Here, 91 smokers participated in a functional magnetic resonance imaging session and a tailored smoking-cessation program. We found that increases in activation in self-related processing regions, particularly dorsomedial prefrontal cortex, to tailored messages predicted quitting during a 4-month follow-up.
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This work was supported by National Institute of Drug Abuse grant R21-DA024429-01 to H.F.C. and V.J.S.
Victor J Strecher is the Chief Visionary Officer and Founder of HealthMedia, a company that develops and licenses computer-tailored health promotion, disease prevention and disease management tools.
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Chua, H., Ho, S., Jasinska, A. et al. Self-related neural response to tailored smoking-cessation messages predicts quitting. Nat Neurosci 14, 426–427 (2011). https://doi.org/10.1038/nn.2761
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