Motor-skill practice drives subsequent offline activity in functionally related resting human brain networks. We investigated the manner in which offline neural networks are modulated by practice structures that affect motor-skill retention. Interference to dorsolateral-prefrontal cortex (DLPFC), but not to primary motor cortex (M1), after variable practice attenuated motor-skill retention, whereas interference to M1, but not to DLPFC, after constant practice attenuated motor-skill retention. We conclude that neural substrates of motor-memory consolidation are modulated by practice structure.
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We thank E.M. Robertson for his thoughtful and constructive comments on an earlier version of the manuscript. The research was supported by a grant from the North American Society for the Psychology of Sport and Physical Activity and an Oakley Fellowship from the Graduate School of the University of Southern California.
The authors declare no competing financial interests.
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Kantak, S., Sullivan, K., Fisher, B. et al. Neural substrates of motor memory consolidation depend on practice structure. Nat Neurosci 13, 923–925 (2010). https://doi.org/10.1038/nn.2596
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