Bacterial specialized metabolites are bioactive molecules with antibacterial or other activities that are of tremendous clinical use. New work has revealed that transcript elongation is a distinct and widespread point of secondary metabolic gene regulation, which has implications for expanding drug discovery.
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Nodwell, J. Antimicrobials: Expressing antibiotic gene clusters. Nat Microbiol 2, 17061 (2017). https://doi.org/10.1038/nmicrobiol.2017.61