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Bacterial pathogenesis: Legionella phosphoinositide tailoring

Nature Microbiology volume 2, Article number: 17013 (2017) Cite this article

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A newly identified phosphoinositide kinase helps to generate phosphatidylinositol 4-phosphate (PtdIns4P) on the vacuolar membrane of the intracellular pathogen Legionella pneumophila. Sequential effector protein cooperation explains the unusual enrichment of PtdIns4P on the Legionella-containing vacuole.

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Figure 1: LepB-mediated modulation of the LCV.

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Authors and Affiliations

  1. Elizabeth L. Hartland is in the Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Victoria, Melbourne 3000, Australia

    Elizabeth L. Hartland

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  1. Elizabeth L. Hartland
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Correspondence to Elizabeth L. Hartland.

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The author declares no competing financial interests.

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Hartland, E. Bacterial pathogenesis: Legionella phosphoinositide tailoring. Nat Microbiol 2, 17013 (2017). https://doi.org/10.1038/nmicrobiol.2017.13

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