Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Fungal pathogenesis: Host modulation every which way

The plant pathogenic fungus Fusarium oxysporum secretes an effector that is similar to a plant peptide hormone, underscoring the variety of mechanisms that plant pathogens have evolved to tamper with host physiology.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Fusarium oxysporum secretes a RALF peptide to induce extracellular alkalinization of plant roots.


  1. Fisher, M. C. et al. Nature 484, 186–194 (2012).

    Article  CAS  Google Scholar 

  2. Win, J. et al. Cold Spring Harb. Symp. Quant. Biol. 77, 235–247 (2012).

    Article  CAS  Google Scholar 

  3. Masachis, S. et al. Nature Microbiol. 1, 16043 (2016).

    Article  CAS  Google Scholar 

  4. Chanclud, E. & Morel, J.-B. Mol. Plant Pathol. (2016).

    Google Scholar 

  5. Chanclud, E. et al. PLOS Pathogens 12, e1005457 (2016).

    Article  Google Scholar 

  6. Prusky, D., McEvoy, J. L., Leverentz, B. & Conway, W. S. Mol. Plant Microbe Interact. 14, 1105–1113 (2001).

    Article  CAS  Google Scholar 

  7. Prusky, D. & Yakoby, N. Mol. Plant Pathol. 4, 509–516 (2003).

    Article  CAS  Google Scholar 

  8. Pearce, G., Moura, D. S., Stratmann, J. & Ryan, C. A. Jr Proc. Natl Acad. Sci. USA 98, 12843–12847 (2001).

    Article  CAS  Google Scholar 

  9. Haruta, M., Sabat, G., Stecker, K., Minkoff, B. B. & Sussman, M. R. Science 343, 408–411 (2014).

    Article  CAS  Google Scholar 

  10. Rodriguez, E., El Ghoul, H., Mundy, J. & Petersen, M. FEBS J. 283, 1385–1391 (2015).

    Article  Google Scholar 

  11. Momany, M., Di Pietro, A., Alexander, W. G., Barker, B. M., Harb, O. S., Kamoun, S., Martin, F., Pires, J. C., Stajich, J. E., Thomma, B. P. H. J. & Unruh, S. G3 5, 2523–2525 (2015).

    Article  Google Scholar 

  12. Lambert, D. H. & Loria, R. Int. J. Syst. Evol. Microbiol. 39, 393–396 (1989).

    Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding authors

Correspondence to Sophien Kamoun or Cyril Zipfel.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kamoun, S., Zipfel, C. Fungal pathogenesis: Host modulation every which way. Nat Microbiol 1, 16075 (2016).

Download citation

  • Published:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing