Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Bacterial pathogenesis: A sand grain in antigen processing

This article has been updated

An effector protein secreted by the intracellular human pathogen Mycobacterium tuberculosis impairs antigen processing in targeted phagocytic cells, resulting in evasion from immune surveillance by a dedicated adaptive immune response.

This is a preview of subscription content

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Figure 1: Impairment of M. tuberculosis antigen presentation by EsxGH.

Change history

  • 14 July 2017

    In the PDF version of this article previously published, the year of publication provided in the footer of each page and in the 'How to cite' section was erroneously given as 2017, it should have been 2016. This error has now been corrected. The HTML version of the article was not affected.

References

  1. 1

    Armstrong, J. A. & Hart, P. D. J. Exp. Med. 134, 713–740 (1971).

    CAS  Article  Google Scholar 

  2. 2

    Portal-Celhay, C. et al. Nat. Microbiol. 2, 16232 (2016).

    Article  Google Scholar 

  3. 3

    Henne, W. M., Buchkovich, N. J. & Emr, S. D. Dev. Cell 21, 77–91 (2011).

    CAS  Article  Google Scholar 

  4. 4

    Hurley, J. H. Crit. Rev. Biochem. Mol. Biol. 45, 463–487 (2010).

    CAS  Article  Google Scholar 

  5. 5

    Philips, J. A. et al. Proc. Natl Acad. Sci. USA 105, 3070–3075 (2008).

    CAS  Article  Google Scholar 

  6. 6

    Philips, J. A., Rubin, E. J. & Perrimon, N. Science 309, 1251–1253 (2005).

    CAS  Article  Google Scholar 

  7. 7

    Mehra, A. et al. PLoS Pathog. 9, e1003734 (2013).

    Article  Google Scholar 

  8. 8

    Groschel, M. I. et al. Nat. Rev. Microbiol. 14, 677–691 (2016).

    CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Olivier Neyrolles.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Neyrolles, O. Bacterial pathogenesis: A sand grain in antigen processing. Nat Microbiol 2, 16234 (2017). https://doi.org/10.1038/nmicrobiol.2016.234

Download citation

Search

Quick links